The principle of HIFU tumor treatment

The principle of HIFU piezo ceramic tumor treatment is to concentrate the ultrasound energy into the disease tissue by a certain focusing method.due to the strong energy deposition of the focal point, makes the focal region in a short time (0.5-5s).The target tissue temperature rises above 60C, which is causing acute irreversible necrosis, thereby achieving destruction.A new treatment that alters the purpose of the tissue without harming the surrounding normal tissue. This therapy is applicable for superficial tissue treatment, it can also treat the deep tissues in the body. It is currently non-invasive treatment for deep tumors.One of the most effective methods has become a hot spot for many researchers to pay attention to research. With the opening of the technology.With the continuous development of hair and application research, ultrasound HIFU piezo ceramics technology has gradually moved to the practical stage.

The application of high intensity focused ultrasound technology to the treatment was first applied to neurosurgery by Cutnn in 1942.Research, Horvath began research on the treatment of human sarcoma with ultrasound in 1944, a Burov in 1956.It is proposed that high-intensity focused ultrasound for short-term exposure will be better than low-intensity ultrasound for long-term exposure, Hickey used HIFu to perform pituitary destruction in 5 patients with advanced breast cancer.Adjuvant therapy for advanced breast cancer. Since 1975, a large number of people have used ultrasonic high focusing piezo to treat tumors.Experiments in the treatment of glioma, sarcoma, hepatoma, adenocarcinoma and prostate cancer in mice.Obtained a positive result at the system cancer center of the University of Texas (USA)Around 1980, 69 cases of sarcoma, melanoma, adenoma, squamous cell tumor and other cancer cases were used simply.Ultrasound hyperthermia, the results of complete remission is accounted for 9%, partial remission accounted for 36%, a total of 45%. At the time because Limitations of imaging and localization techniques, and the therapeutic ultrasound energy used is lower, and ultrasound hyperthermia is not widely available.

Ultrasonic heating technology, ultrasonic imaging technology and computer control technology since the 1980s.The development of related technologies has made ultrasonic heating positioning possible, which has promoted the development of HIFU equipment. The United States funded the National Cancer Institute to start researching Hifu piezoelectric crystal technology; in Japan, now the National Association of Hyperthermia.There are more than 1,500 people In the 1990s, ultrasound technology has penetrated into the inter-tissue tissue to heat,This opens up a new field of ultrasound oncology treatment in the United States .which has developed a treatment for rectal cancer and bladder.Ultrasonic hyperthermia equipment for skin cancer, but the actual effect is not very satisfactory. Now the experiment of HIFU technology.Significant progress has been made in research and clinical applications, and glaucoma and benign prostatic hyperplasia have begun to be treated clinically.it is early prostate cancer, advanced liver cancer, breast cancer, osteosarcoma, soft tissue sarcoma, kidney cancer, etc.The disease has achieved good therapeutic results.