What’s the high intensity focused ultrasound

Publish Time: 2018-10-12     Origin: Site


With the development of medical technology, high intensity focused ultrasound (HIFU) has been widely developed at home and abroad as a new non-invasive tumor treatment technology, and has achieved significant clinical results, especially in the treatment of uterine fibroids and good clinical results. The introduction of high-intensity focused ultrasound (HIFU) thermal ablation tumor treatment technology provides an effective, non-invasive, painful, safe and economical tumor treatment experience. Ultrasound is a high-frequency mechanical vibration wave with focusability, tissue penetration and energy deposition. Using the tissue penetration and energy deposition of ultrasound, the ultrasound generated in vitro is focused on the diseased tissue (the therapeutic target) in vivo, and the purpose of treating the disease is achieved by the mechanical, thermal and cavitation effects of ultrasound. The mode of action is similar to the principle that the sunlight is focused by the magnifying glass and causes them placed at the focus to burn.


The principle of ultrasound HIFU ceramic transducer is that the energy of the focused ultrasound at the non-treated through which is not sufficient to cause damage of the tissue. At its focus point, due to the high sound intensity, the temperature of the tissue is instantaneously raised to 65 ~ 100 °C by the thermal effect of ultrasound, which leads to protein denaturation and coagulative necrosis of tissue cells. At the same time, it is also caused by the cavitation effect of ultrasound.They are interstitial fluid, intercellular fluid and intracellular gas molecules form bubbles under the action of ultrasonic positive and negative pressure phases, and then contract and expand to eventually blast, and the energy generated causes cell damage and necrosis. The shape and size of the focused ultrasound focal spot and the effects of tissue on ultrasound and its counteraction play a decisive role in the depth of ultrasound treatment,they are the extent of tissue damage and the degree of injury. Therefore, by setting the parameters of the ultrasonic transducer, the purpose of targeting the lesion can be achieved, and the tissue surrounding the treatment target is not damaged, thereby achieving the goal of non-invasive treatment.


Ultrasound ablation is the use of ultrasound to pass through human tissue and focus on specific target areas, which concentrate energy to sufficient intensity,to achieve a transient high temperature in the focus area, destroy the target tissue, and appear to be coagulative necrosis in histopathology Also called ablation. Thereby, the purpose of destroying the lesion area is achieved, and the tissue outside the lesion area is not damaged.


Treatment characteristics:


1 Image monitoring: Real-time monitoring of ultrasound images is used to determine the target tumors that are planned to be selected. The entire treatment process of 7Mhz HIFU piezo transducer is controlled by the system and provides timely feedback on treatment outcomes.
2 Accuracy: The energy at the focus causes coagulative necrosis of the tissue at the focus and no damage to the surrounding tissue or tissue on the acoustic channel. The boundary between the treated and non-treated areas is only 6 to 10 cells wide.
3 Free movement: focus and monitoring the free movement of the probe in the space,which can achieve stereo combined scanning treatment, physicians can choose a fast, flexible and effective treatment according to different patients and different tumors.
4 Thorough treatment: The treatment planning software for the focused ultrasound oncology treatment system can help the physician accurately lock and resect the entire tumor tissue. There is no upper limit to the volume of tumor that may be treated.
5 Controllable treatment: Real-time imaging technology provides video feedback to physicians throughout the treatment process, HIFU piezo for laser machine is adjusting the dose at any time based on digital grayscale changes.


The advantage of therapeutic is that the whole treatment process is non-invasive, no bleeding, no need for anesthesia, and truly realizes the treatment of tumors from the body in vitro and kills tumor tissues. During the treatment, the ultrasound is used to treat the head, and the depth of focus of the HIFU piezoelectric element is changed. The point-line-face-body combination scanning method is used to perform a conformal ablation of the entire fibroid. The advantages of high-energy focused ultrasound therapy are non-invasive treatment in vitro, completing destruction of the body lesions; there is no surgery, no radioactive damage, no surgical exposure and puncture guidance;there is no damage to the tissue passing through the ultrasound or the normal structure outside the target area. The treatment with low total cost significantly shortens the length of hospital stay; there is no blood transfusion during treatment; significantly reduces the patient during surgery,

Possible risks of focused ultrasound therapy:
(1) nerve damage;
(2) Adverse reactions in the static pain of the town;
(3) Mild burns on the skin; careful preparation before treatment, real-time monitoring during treatment can avoid the above risks.


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